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LPS is a potent toll-like receptor (TLR)4 signaling activator and already described to activate the inflammatory compound in human atherosclerotic lesions ex vivo. 22 The pathophysiologic aspect of TLR4 in atherogenesis relates to its additional ligands, known autoantigens in atherogenesis such as heat shock protein 60 from Chlamydia pneumoniae or oxidized low density lipoprotein. Statistical Analysis A priori it was expected that Aboriginal and TSI people would differ significantly in their anthropometric and metabolic characteristics, so comparisons quest of all variables were made across Aboriginal versus TSI ethnicity. The remaining H atoms were positioned geometricallyFigures Open in a separate window Fig. 1. Part of the polymeric chain of the title compound, with the atom-numbering scheme.

Further studies, incorporating other diagnostic parameters, may be needed belooking fore a more logical conclusion can be drawn, since the D-dimer is not a specific test. ?Footnotes Disclosure The authors report no conflicts of interest in this work.

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